Appendicitis is a condition where the
appendix becomes swollen, inflamed, and filled with pus. The appendix is a
small finger-shaped pouch on the right side of the abdomen, connected to the
colon.
The exact role of the appendix is not clear.
It may be an area that hosts friendly bacteria, which help digestion and fight
infection.
It may also be related to the immune system
and influence the body's ability to fight off infection.
Appendicitis probably happens because either
a stomach infection moves to the appendix or a hard piece of stool becomes
trapped in the appendix, causing infection
Appendicitis can occur at any age, most
commonly ranging from older children to adults in their 30s. It most commonly
occurs in the second decade of life. More than 250,000 appendectomies (removal of the appendix) are
performed in the United States each year.
Fast facts on appendicitis
Scientists are still debating the function of
the appendix.
Symptoms of appendicitis include a
progressively worsening pain, nausea, and vomiting.
Often, surgery is the best course of action.
More than a quarter of a million Americans
have an appendectomy each year.
Signs and symptoms
The first sign of appendicitis is often pain
across the abdominal area.
As the infection progresses, the location of
the pain becomes more defined in the lower right-hand side of the abdomen, an
area known as McBurney's point.
The following symptoms are common:
progressively worsening pain
painful coughing or sneezing
nausea
vomiting
diarrhea
inability to pass gas (break wind)
fever
constipation
loss of appetite
Anybody who experiences a progressively
worsening pain in the abdomen should seek medical attention. Other conditions
may have similar symptoms, such as a urinary tract
infection. Even so, they all require urgent medical attention.
Diagnosis
Around half of all patients with appendicitis
do not have typical symptoms, and this can make it hard to diagnose. For
example, the pain is not always located in the right lower quadrant of the
abdomen.
Additionally, other conditions may have
similar symptoms, such as:
gastroenteritis
urinary tract infection
ectopic pregnancy
Crohn's disease
kidney stones
Not everybody's appendix is in the same
place. Sometimes it is located behind the colon, behind the liver, or in the
pelvis.
A doctor will examine the patient and ask
some questions related to their symptoms. They may apply pressure to the area
to see if it worsens the pain.
If the doctor detects typical signs and
symptoms, they will diagnose appendicitis. If not, further tests will be
ordered.
Tests may include:
blood tests, to check for infection
an MRI, CT, or ultrasound scan,
to see if the appendix is inflamed
urine tests, to identify a kidney or bladder
infection
Researchers at the Proteomics Center at
Children's Hospital in Boston, MA, have demonstrated that a protein detectable in urine could
be useful as a biomarker for appendicitis.
Sometimes, a doctor will decide to surgically
remove the appendix because it is too risky to wait for tests to confirm the
diagnosis.
Source: Medical News Today
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