Human papillomavirus is the
most common sexually transmitted infection in the United States. Out of the
more than 100 different types of the virus, around 40 can infect the mouth,
throat, and genitals.
In most cases, the immune
system clears human papillomavirus, or HPV, from the body
before it can cause a full infection and symptoms.
Some strains of HPV result in
harmless oral lesions that usually resemble common warts,
but doctors have linked some others with oral cancers.
How common is HPV?
HPV and oral HPV are very
common. According to the Centers for Disease Control and Prevention (CDC),
around 10
percent of men and 3.6 percent of woman in the U.S. have oral
HPV.
What causes it and how
does it spread?
Oral HPV spreads mostly through
oral sex and mouth-to-mouth contact between people.
During mouth-to-genital or
mouth-to-mouth contact, HPV particles travel via infected saliva or mucus
through an open cut or sore in an uninfected person's mouth or throat.
Mothers can also pass HPV to
their children. Most research indicates HPV may also sometimes spread via oral
contact with contaminated utensils or medical instruments.
The immune system usually
destroys invading HPV particles before they cause an infection. Healthy immune
systems usually resolve HPV infections within 1 to 2 years.
However, some HPV infections can persist.
Risk factors
The greatest risk factor for
developing oral HPV is oral sex or having mouth-to-mouth contact with someone
infected with HPV.
Researchers are still trying to
determine the full range of risk factors for oral HPV, but some known factors
include:
not using proper protection
during oral sex
deep kissing
having multiple sexual partners
smoking and tobacco products
engaging in sexual activities
from a young age
drinking alcohol
sharing drinks and utensils
Symptoms and what it
looks like
Many people with minor cases of
HPV do not have any apparent symptoms. There are also many strains of HPV that
can each cause slightly different symptoms.
When it does cause a productive
infection, HPV can cause growths that are:
small and hard
white, pink, flesh-colored, or
red
slightly raised or flat
painless
usually slow growing
smooth or slightly calloused
single or multiple in a
cauliflower- or cobblestone-like mass
anywhere in the mouth, but
frequently on the tongue, soft palate at the back or roof of the mouth, and
lips
HPV is the leading cause of
oropharyngeal, or oral cavity, cancers, although this complication is rare.
This is especially true for those infections that involve the tongue and base
of the tongue into the throat.
The type of HPV called HPV 16
causes most oral cancers related to HPV.
Oral cancers tend to cause
obvious symptoms, especially as they progress. Signs and symptoms of oral cancer include:
a sore or painful bump that
does not go away within 3 weeks
difficulty swallowing or the
feeling of things sticking together when trying to swallow
discoloration (red, white,
black) of the soft tissues in the mouth
swollen but painless tonsils
a lump in the mouth that lasts
for at least 3 weeks
a lump that a person feels on
the outside of the neck
pain when chewing
chronic sore throat or hoarseness
chronic cough
numbness or tingling in the
lips or tongue
a unilateral, or one-sided,
earache that lasts for more than 3 weeks
drooling
Diagnosis
There is currently no easy way
for a doctor to diagnose HPV. The most useful test for HPV is a polymerase
chain reaction (PCR) test.
A PCR test takes a tiny
fragment of DNA extracted from cells in a sample of mucus and amplifies it,
making countless identical copies. Having so many copies of the DNA fragment
allows scientists to look inside cells and detect minute quantities of abnormal
or viral DNA.
In rare cases, when lesions are
present in the mouth, a doctor may be able to diagnose HPV by examination alone.
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