Cannabidiol, or CBD, is
a natural compound that has gained popularity in recent years, thanks in part
to a growing body of research into its potential health benefits, which may
include treating depression. The initial results of some studies into CBD and
depression look promising.
CBD is one of more
than 100 compounds called cannabinoids. These occur naturally in the cannabis
plant.
While CBD is similar
to tetrahydrocannabinol (THC), the two compounds act differently in the body.
THC is responsible for the feelings of euphoria, or the "high," that
a person experiences while using cannabis.
CBD does not have
these effects on the body — it does not cause a high or feelings of euphoria.
In this article, learn
about the potential for CBD to help relieve the symptoms of depression. CBD may not be right for everyone,
and there are some other things to consider before using CBD treatment for any
condition.
CBD for depression
Depression and anxiety disorders are
common mental
health conditions that can have lasting effects on a person's
health, social life, ability to work, and overall well-being.
A doctor may prescribe
pharmaceutical drugs to help a person treat or manage depression. Many of these
drugs have difficult side effects, such as mood swings, sleeplessness, and
sexual dysfunction.
CBD has shown promise
in initial studies as a treatment for both depression and anxiety, and it may
cause fewer side effects in some people.
The findings of research from 2014 may
help explain why CBD could be useful in treating depression. They indicate
that, in most studies, CBD appears to have a positive interaction with serotonin receptors in the brain.
Serotonin impacts a
range of functions in the body, including a person's emotional state and
feelings of well-being or happiness. Keeping serotonin levels balanced is often
a key therapy for people with depression.
What the research says
Testing in animal
models has provided some evidence for the use of CBD to help treat depression.
According to the
authors of the 2014 review,
results from a variety of studies indicate that CBD appears to act as an antidepressant and
antianxiety compound in animal models of depression.
Authors of a review from 2018 also
noted that many studies have shown the anti-stress and antidepressant activity
of CBD in animal models.
The compound exhibits
a clear anti-stress effect after short- or long-term use. In certain tests, CBD
acted as an antidepressant.
The authors also found
that the compound worked without activating the brain's endocannabinoid
receptors directly, which may indicate that there is less risk of CBD becoming
habit-forming, or addictive.
Researchers have even
studied CBD's potential to help reduce cravings in
people with opioid use disorder.
In a study from 2018,
researchers indicated that CBD has promise as a fast-acting antidepressant.
Most researchers
conducting animal studies of CBD call for more direct research in humans, but
their initial results are an essential step toward establishing how CBD works
in the body.
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CBD for panic and anxiety
Some studies in humans
show that CBD may be useful for other issues commonly associated with
depression, such as anxiety or panic disorder.
A 2017 review of the
potential benefits of CBD for panic disorder found some positive results.
According to the
authors, panic disorder affects approximately 5 percent of the worldwide
population and causes unexpected and recurring panic attacks.
In human models, a
single dose of 300 milligrams (mg) of CBD caused a notable decrease in anxiety
levels after a simulated public speaking test, according to one study in the
review.
Another found that 600
mg of CBD caused a significant reduction of anxiety measures in people with social anxiety disorder.
Source: Medical News Today
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