|
N
|
ew research reveals that being
overweight, obese, or severely obese may improve a person's chances of
surviving after a stroke.
Being obese or overweight may have
its advantages, suggests one new study.
Obesity is a "serious medical condition" that can lead to various complications.
These might include atherosclerosis and heart disease, diabetes, cancer, and even sleep disorders.
Being overweight may also raise
the risk of all-cause mortality and mental health conditions such
as depression and anxiety.
Despite this, some researchers
maintain that excessive body fat can have a protective cardiovascular effect.
In fact, the authors of a 2002
reference paper coined the phrase "obesity paradox" to
describe the observation that people with a higher body mass index (BMI) are less likely to die from cardiovascular
conditions than people with a normal weight.
Since then, the theory has been the
subject of much controversy.
However, new evidence appears to support it.
Dr. Zuolu Liu — from the University
of California, Los Angeles — and her colleagues wanted to see how the obesity
paradox applies to stroke. Previous research
into the same issue, explain the researchers, yielded mixed results.
They will present their new findings at
the American Academy of Neurology's 71st Annual Meeting, which
this year takes place in Philadelphia, PA.
Up to 62
percent lower chance of death
Dr. Liu explains the motivation for
their study, saying, "It was first noticed that carrying extra weight may
play a role in survival for people who had suffered from kidney and heart
disease, so we felt the need to investigate whether it also was tied to
improved stroke survival."
To do so, the researchers examined
1,033 people who had experienced an ischemic stroke — that is, a condition
wherein the arteries that pump blood to the brain are blocked.
The participants were 71 years old,
on average, and their average BMI was 27.5. People whose BMI is between 25 and
29.9 are considered overweight,
while a BMI of over 29.9 indicates obesity.
Dr. Liu and team grouped the
participants into five categories — "underweight, normal, overweight,
obese, and severely obese" — according to their BMI. The researchers
monitored the participants' survival and recovery for 3 months after their stroke.
Overall,
people with severe obesity had a 62 percent lower chance of dying from a stroke
than people with a normal BMI, people with obesity had a 46 percent lower
chance of death, and those who were overweight had a 15 percent lower chance of
dying.
However, those who were underweight
had a 67 percent higher chance of dying following a stroke than people with a
normal BMI. Dr. Liu and colleagues conclude:
"Outcome from acute ischemic stroke is characterized by
an obesity paradox: elevated BMI is associated with reduced 3-month mortality
over all, and reduced disability over most weight ranges."
The study was observational, so it
cannot account for causality. However, a "possible explanation is that
people who are overweight or obese may have a nutritional reserve that may help
them survive during prolonged illness," says Dr. Liu.
The researchers also caution that
their results may not be applicable to the general population, as the study
sample was limited to people from southern California.
"More research is needed to
investigate the relationship between [BMI] and stroke," says Dr. Liu.
No comments:
Post a Comment