Recently, the government of the United Kingdom received ethics approval to run the world’s first SARS-CoV-2 human challenge study. In this article, we explain what human challenge studies are and what insights they can provide.
As it stands, 11 COVID-19 vaccines have been authorized, across several countries. Waiting in the wings are at least 80 vaccine candidates, 20 of which are in phase 3 clinical trials.
It is truly incredible that within 1 year of discovering a new virus, we already have a range of experimental and authorized vaccines, but this is not the end of the story.
There is still room to improve existing vaccines. Additionally, having a range of companies manufacturing vaccines can be beneficial — if problems arise with one supply chain, another can take its place.
It may also be the case that certain vaccines work better in some populations than in others.
To help streamline and improve vaccine testing and discovery, the U.K. government is funding human challenge studies.
Source: Medical News Today
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