Vitamin B12 is an important B vitamin. It is crucial for nerve tissue health, brain function, and the production of red blood cells. Cobalamin is another name for vitamin B12.
A deficiency or insufficiency can occur when levels of vitamin B12 become too low to meet the demands of the body. This can lead to a number of symptoms and can even progress to irreversible neurological issues if left untreated.
In the United States and United Kingdom, approximately
Vitamin B12 is a water-soluble vitamin, like all other B vitamins. This means it can dissolve in water and travel through the bloodstream. The body can store vitamin B12 for up to 4 years, and it can get rid of any excess or unwanted vitamin B12 in the urine.
Vitamin B12 is the largest and most structurally complicated vitamin. It occurs naturally in animal products like meat and eggs, and manufacturers can produce it through bacterial fermentation synthesis.
This article explores the functions of vitamin B12, how a person would know they are not consuming enough vitamin B12, and how to increase intake
Vitamin B12 is crucial to various bodily processes, including :
- normal functioning of the brain and nervous system
- cognitive functioning (ability to think)
- formation of red blood cells and anemia prevention
- helping create and regulate DNA
- possibly preventing congenital abnormalities
- helping protect the eyes from macular degeneration
- necessary for energy production
Vitamin B12 is essential for healthy blood. When the body does not have enough B12, it leads to decreased normal red blood cell production (anemia), which impairs oxygen delivery.
Megaloblastic anemia, also called nutritional-deficiency anemia, is a type of anemia caused by B12 or folate deficiency. Megaloblastic anemia is characterized by impaired DNA synthesis and the formation of large, abnormal, immature red blood cells.
Vitamin B12 is crucial to various bodily processes,
- normal functioning of the brain and nervous system
- cognitive functioning (ability to think)
- formation of red blood cells and anemia prevention
- helping create and regulate DNA
- possibly preventing congenital abnormalities
- helping protect the eyes from macular degeneration
- necessary for energy production
Vitamin B12 is essential for healthy blood. When the body does not have enough B12, it leads to decreased normal red blood cell production (anemia), which impairs oxygen delivery.
Megaloblastic anemia, also called nutritional-deficiency anemia, is a type of anemia caused by B12 or folate deficiency. Megaloblastic anemia is characterized by impaired DNA synthesis and the formation of large, abnormal, immature red blood cells.
Intake requirements
Who is at risk?
Several groups of people may be at an increased risk of vitamin B12 deficiency.
Vegans face a risk of vitamin B12 deficiency, as their diet excludes animal-sourced food products. Pregnancy and lactation can worsen deficiency in vegans. Unless a vegan diet is carefully planned, it is difficult to get enough vitamin B12 through plant foods alone. For this reason, it is recommended for those following vegan diets to supplement with B12.
People with pernicious anemia may lack vitamin B12. Pernicious anemia is an autoimmune disease that affects the blood. Patients with this disorder do not have enough intrinsic factor (IF), a protein in the stomach that allows the body to absorb vitamin B12.
Other at-risk groups include people with small intestine problems, for example, an individual with a surgically shortened small intestine. Crohn’s disease is also a risk factor for vitamin B12 deficiency due to frequent involvement of the terminal ileum.
Gastritis, celiac disease, and inflammatory bowel disease (IBD) may lead to a deficiency because these conditions reduce nutrient absorption.
People with chronic alcohol use disorder may lack vitamin B12, as their bodies may not absorb nutrients efficiently.
People with diabetes who are treated with metformin should have their B12 levels tested by their healthcare professional regularly. This is because metformin reduces the absorption of vitamin B12.
Treatment for vitamin B12 deficiency includes oral vitamin B12 supplements or vitamin B12 injections.
Several groups of people may be at an
increased risk of vitamin B12 deficiency.Vegans face a risk of vitamin B12 deficiency, as their diet excludes animal-sourced food products. Pregnancy and lactation can worsen deficiency in vegans. Unless a vegan diet is carefully planned, it is difficult to get enough vitamin B12 through plant foods alone. For this reason, it is recommended for those following vegan diets to supplement with B12.
People with pernicious anemia may lack vitamin B12. Pernicious anemia is an autoimmune disease that affects the blood. Patients with this disorder do not have enough intrinsic factor (IF), a protein in the stomach that allows the body to absorb vitamin B12.
Other at-risk groups include people with small intestine problems, for example, an individual with a surgically shortened small intestine. Crohn’s disease is also a
risk factor for vitamin B12 deficiency due to frequent involvement of the terminal ileum.Gastritis, celiac disease, and inflammatory bowel disease (IBD) may
lead to a deficiency because these conditions reduce nutrient absorption.People with chronic alcohol use disorder may lack vitamin B12, as their bodies may not absorb nutrients efficiently.
People with diabetes who are treated with metformin should have their B12 levels tested by their healthcare professional regularly. This is because metformin reduces the absorption of vitamin B12.
Treatment for vitamin B12 deficiency includes oral vitamin B12 supplements or vitamin B12 injections.
Vitamin B12 is an essential vitamin mainly found in animal products. Most adults require 2.4 mcg daily.
The body needs vitamin B12 for normal function of the brain and nervous system, the formation of red blood cells, and other critical processes.
Deficiencies in vitamin B12 can lead to symptoms like headaches, fatigue, and digestive problems and can even lead to nerve damage and cognitive issues.
Some people are more at risk of deficiencies, such as older adults and those who do not absorb nutrients well. Vegans may also have a deficiency risk, as their diet excludes many B12 sources.
Most people who eat a balanced diet receive enough B12. For others, doctors may recommend oral supplements or injections.
Source - Medical News today
Vitamin B12 is an essential vitamin mainly found in animal products. Most adults require 2.4 mcg daily.
The body needs vitamin B12 for normal function of the brain and nervous system, the formation of red blood cells, and other critical processes.
Deficiencies in vitamin B12 can lead to symptoms like headaches, fatigue, and digestive problems and can even lead to nerve damage and cognitive issues.
Some people are more at risk of deficiencies, such as older adults and those who do not absorb nutrients well. Vegans may also have a deficiency risk, as their diet excludes many B12 sources.
Most people who eat a balanced diet receive enough B12. For others, doctors may recommend oral supplements or injections.
Source - Medical News today
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