Friday 5 March 2021

What to know about CBD and sleep

 People have long used the cannabis plant for medicinal and recreational purposes. Compounds called cannabinoids in the plant are responsible for the effects on the brain, and the two most abundant of these are tetrahydrocannabinol (THC) and cannabidiol (CBD).

THC and CBD are both psychoactive, but they affect the brain differently. Unlike THC, CBD is nonimpairing.

People use CBD for a variety of reasons, including reducing seizures, anxiety, and pain.

Some studies have demonstrated that CBD may also be a sleep aid. In this article, we look at whether it works and any associated risks.

In the last decade, growing public interest in the benefits of marijuana, and CBD in particular, has encouraged researchers to study its effects.

Early studies indicate that high dosages of CBD may support sleep.

One investigation found that, compared with a placebo, a CBD dosage of 160 milligrams (mg) increased sleep duration. The researchers also concluded that the placebo, 5 mg of the insomnia drug nitrazepam, and 40, 80, and 160 mg of CBD helped the participants fall asleep.

Levels of cortisol, the stress hormone, typically peak in the morning, but people with insomnia may have high cortisol levels at night. Independent of insomnia, having high cortisol levels at night is associated with an increased number of nighttime awakenings.

In one study on the effects of CBD, researchers found that cortisol levels decreased more significantly when participants took 300 or 600 mg of CBD oil. These results suggest that CBD affects the release of cortisol, possibly acting as a sedative.

A more recent analysis of CBD and sleep recruited 103 participants who had anxiety or poor sleep. The researchers studied the effects of CBD combined with those of other prescribed medications.

The CBD dosages ranged from 25–175 mg. The researchers found that 25 mg was the most effective dosage for anxiety and that addressing troubled sleep required higher dosages.

During the 3-month study, the investigators followed up with the participants monthly. At the first follow-up, 66.7% reported an improvement in sleep, but 25% had worsened sleep. At the second, 56.1% of the participants reported improved sleep, but 26.8% had worsened sleep.

The researchers conclude that although CBD might help people sleep in the short term, the effects may not be sustained.

Source: Medical News Today

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