Anaphylaxis
shock is a dangerous and potentially life-threatening condition caused by an
allergic reaction. Many people use the terms anaphylaxis and anaphylactic shock
to refer to the same thing. Anaphylactic shock, however, is a complication of
anaphylaxis that occurs when the blood pressure drops very low, and the blood
has trouble circulating.
Allergies
occur when a person's immune system overreacts to a harmless substance called
an allergen. This reaction causes the body to release chemicals that lead to
irritation and other symptoms. Usually, allergic reactions are minor, causing
symptoms such as a rash or a runny nose.
When a
person's immune system dramatically overreacts to an allergen, it may release
chemicals that affect multiple systems in the body.
This can throw the person into anaphylaxis.
In some people, anaphylaxis can include anaphylactic shock.
Fast facts on anaphylactic shock:
- As with anaphylaxis, anaphylactic shock is a life-threatening emergency.
- People with a history of anaphylactic reactions are at risk of anaphylactic shock.
- People who have had anaphylactic reactions should always carry an epinephrine injector.
Symptoms of
anaphylactic shock
Most people
develop symptoms of anaphylaxis within a few minutes of eating or being exposed
to an allergen.
Less
frequently, symptoms develop several hours later. The most common symptoms of an
anaphylactic reaction include:
- nose, mouth, skin, or stomach irritation, such as a rash, diarrhea, or congestion
- breathing difficulties or wheezing
- low blood pressure that can cause fainting, dizziness, or confusion
- swelling of the mouth, tongue, or throat
- swollen lips
- a choking sensation or trouble swallowing
In some
people, anaphylactic shock occurs as well as anaphylaxis.
A person will
experience symptoms related to low blood pressure and poor oxygen flow to their
organs if they are in anaphylactic shock.
Someone in
anaphylactic shock may also lose consciousness, lose bowel or bladder function,
or experience chest pain.
Anaphylactic
shock reactions are similar to other forms of medical shock. In someone
experiencing a severe allergic reaction while in a life-threatening situation,
it might not be possible to distinguish anaphylaxis from other causes of shock.
In most people, however, the condition is easily detected because of recent
exposure to an allergen.
Early signs
The early
symptoms of anaphylactic shock vary and may initially seem relatively mild.
They may include hives, itching, or a sense of
dread.
People with a
history of severe allergic reactions often have the same pattern of symptoms
each time they react.
Early warning signs that a
person may be going into anaphylactic shock include:
- turning blue or white
- swelling of lips or face
- grating, grainy cough
- wheezing
- breathing problems
- hives, particularly if over several areas
Treatment
An
epinephrine injector is a primary treatment for people experiencing
anaphylaxis.
Also called
an EpiPen, these injectors carry a single dose of the hormone epinephrine.
Epinephrine
reverses the action of substances produced during the allergic reaction. It can
also prevent the body from going into shock or reverse the process of shock if
it has already started.
The EpiPen is
usually injected directly into the thigh and is only available with a
prescription from a doctor.
People should
call 911 if they are experiencing or suspect they may be experiencing an
anaphylactic reaction.
It is not
safe to treat anaphylaxis at home or be driven to the hospital. If a person
delays treatment, it can be fatal. Treatment always begins with the
administration of epinephrine.
In cases of
severe anaphylactic shock, a person may need additional treatment. This may include the following
therapies and medications:
- administration of oxygen therapy
- intubation with a tube hooked to a machine to help with breathing
- beta-agonist injection to reduce swelling in the respiratory tract
- antihistamines to reduce the severity of the allergic reaction
- vasopressors to narrow blood vessels and raise blood pressure if it becomes dangerously low
- corticosteroids to help block allergic reactions and reduce swelling
- IV fluids for low blood pressure
It is
important for people with a history of anaphylactic reactions to know which
substances or allergens trigger symptoms.
A doctor will
typically recommend allergy testing. This is because people with a history of
anaphylactic reactions to one substance may also have severe allergic reactions
to other allergens. Avoiding these allergens can be lifesaving.
People who
are allergic to substances that cannot be avoided, such as insect stings, may
be able to prevent anaphylaxis with allergy treatment.
Desensitization, also known as
immunotherapy or allergy shots, involves slow and steady exposure to tiny
amounts of an allergen to reduce the risk of an allergic reaction.
People can
ask for a referral to an allergist who can decide whether desensitization is an
option.
What are the causes?
People have
anaphylactic reactions because of allergies.
The body produces proteins that can attack dangerous invaders, including
viruses and bacteria.
A person with
allergies produces immunoglobulin E (IgE) proteins in response to
harmless substances. These substances trigger white blood cells called mast
cells to release specific chemicals, often histamines that cause an allergic
reaction.
Some
allergens are more likely than others to cause such a reaction.
These common
allergens may be:
- insect stings
- foods, including peanuts, walnuts, shellfish, and eggs
- latex
- medications, including penicillin, some anesthesia, and aspirin
However, any
substance a person is allergic to can trigger an anaphylactic reaction.
Source: Medical News Today
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