The main cause of symptoms in PD is a fall in dopamine production in the brain. This affects movement, but it can also affect a person’s thinking and sense of well-being.

This can lead to:

Dementia: This is common in the later stages of the disease. The person may have difficulty remembering things and thinking clearly.

If clumps of protein — Lewy bodies — form in the brain, dementia is more likely. Some people with PD also have the tangles of protein that occur with Alzheimer’s disease.

Sleep problems: These are a core feature of PD. Contributing factors include REM sleep disturbances, the use of some medications, restless leg syndrome, pain, and difficulty turning over in the night.

A person may have difficulty sleeping or staying asleep at night, and they may also be excessively sleepy during the day.

Tiredness: Fatigue and a lack of energy can happen because of sleep problems and also because of the way PD affects movement.

Depression: This is a common problem. It can result from the changes in brain activity and from how the person feels about their condition. Anxiety is another common problem.

Psychosis: This is common in the later stages, and it can affect nearly 1 in 3 people with PD. It can range from minor illusions and vivid dreams to hallucinations, confusion, and paranoia. Hallucinations are usually visual, but some people hear and feel things that are not there.

Sensory changes: People with PD often lose their sense of smell. This can happen long before other symptoms appear. Experts consider it a predictor of PD. Some people experience a numbness, tingling, and prickling in the skin.

Pain: Pain is a common problem with PD, affecting over 60 percentTrusted Source of people with the disease, according to one study. Some people also experience a reduced sense of pain.

A person can have PD for a long time without noticeable symptoms. In addition, many of the symptoms can also occur with other conditions.

This makes it difficult to know when something is wrong. It can also make it hard for a doctor to diagnose PD.

Anyone who notices changes in their movements, thinking, or other bodily functions should see a doctor.

If the diagnosis is PD , early treatment can help reduce most of the symptoms that occur with this condition and improve quality of life.

Source: Medical News Today