Neurons are responsible for
carrying information throughout the human body. Using electrical and chemical
signals, they help coordinate all of the necessary functions of life. In this
article, we explain what neurons are and how they work.
In short, our
nervous systems detect what is going on around us and inside of us; they decide
how we should act, alter the state of internal organs (heart rate changes, for
instance), and allows us to think about and remember what is going on. To do
this, it relies on a sophisticated network — neurons.
It has been
estimated that there are around 86 billion neurons in the brain; to reach
this huge target, a developing fetus must create around 250,000
neurons per minute.
Each neuron is
connected to another 1,000 neurons, creating an incredibly complex network of
communication. Neurons are considered the basic units of the nervous system.
Because they are
Neurons, sometimes
called nerve cells, make up around 10 percent of the brain; the rest consists
of glial cells and astrocytes that support and nourish neurons.
What do neurons
look like?
Neurons can only be seen using a microscope and
can be split into three parts:
Soma (cell body) — this
portion of the neuron receives information. It contains the cell's nucleus.
Dendrites — these thin
filaments carry information from other neurons to the soma. They are the
"input" part of the cell.
Axon — this long projection
carries information from the soma and sends it off to other cells. This is the
"output" part of the cell. It normally ends with a number of synapses
connecting to the dendrites of other neurons.
Both dendrites and
axons are sometimes referred to as nerve fibers.
Axons vary in
length a great deal. Some can be tiny, whereas others can be over 1 meter long.
The longest axon is called the dorsal root ganglion (DRG), a cluster of
nerve cell bodies that carries information from the skin to the brain. Some of
the axons in the DRG travel from the toes to the brain stem — up to 2 meters in
a tall person.
Types of neurons
Neurons can be
split into types in different ways, for instance, by connection or function.
Connection
Efferent neurons — these take
messages from the central nervous system (brain
and spinal cord) and deliver them to cells in other parts of the body.
Afferent neurons — take
messages from the rest of the body and deliver them to the central nervous
system (CNS).
Interneurons — these
relay messages between neurons in the CNS.
Function
Sensory — carry signals from the
senses to the CNS.
Relay — carry signals from one
place to another within the CNS.
Motor — carry signals from the
CNS to muscles.
How do neurons carry a
message?
If a neuron receives a large number of inputs
from other neurons, these signals add up until they exceed a particular
threshold.
Once this
threshold is exceeded, the neuron is triggered to send an impulse along its
axon — this is called an action potential.
An action
potential is created by the movement of electrically charged atoms (ions)
across the axon's membrane.
Neurons at rest
are more negatively charged than the fluid that surrounds them; this is
referred to as the membrane potential. It is usually -70 millivolts (mV).
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